Advanced cell-based therapies are often delivered to the patient frozen. Hence, any technology which increases the number of recovered, viable, cells post-thaw may improve clinical outcomes or allow more treatments per donation. We have previously shown strategies to protect cells during freezing. In this latest work, in collaboration with Cytiva, the team show that incubating a model … Continue reading Amino Acid Improves T-Cell Cryopreservation
Perfect Glyco-Clusters Published in ACS AMI!!
We have a major interest in developing synthetic mimics of the glycocalyx (sugars on outside of all our cells) and glycoproteins. A key challenge is that most mimics are heterogeneous - e.g. polymers and nanoparticles have dispersity: hence you 'cannot make the same material twice' and you dont know exactly the what the structure will … Continue reading Perfect Glyco-Clusters Published in ACS AMI!!
PhD Vacancies
We have 3 PhD vacancies to start later in 2023. These span both synthesis and cell culture. Go to the 'join us' page for more details.
Cryopreservation of Spheroids Published in ChemCommun Our latest work, developing technologies to allow us to bank complex 3D tissue models, with a long term aim of them being 'ready to use' and 'off the shelf' to help researchers replace animal models, has been published. In this we prepare the cells for freezing by proline pre-conditioning … Continue reading
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